Mary Sullivan is raped and strangled to death in her Boston apartment. The killer left a card reading “Happy New Year” leaning against her foot. Sullivan would turn out to be the last woman killed by the notorious Boston Strangler, Albert DeSalvo, who had terrorized the city between 1962 and 1964, raping and killing 13 women.

On January 11, 1964, United States Surgeon General Luther Terry releases a groundbreaking government report announcing a definitive link between smoking and cancer.

The U.S. State Department angrily accuses the Soviet Union of shooting down an American jet that strayed into East German airspace. Three U.S. officers aboard the plane were killed in the incident. The Soviets responded with charges that the flight was a “gross provocation,” and the incident was an ugly reminder of the heightened East-West tensions of the Cold War-era.

Stanley Kubrick’s black comic masterpiece, Dr. Strangelove or: How I Learned to Stop Worrying and Love the Bomb opens in theaters to both critical and popular acclaim. The movie’s popularity was evidence of changing attitudes toward atomic weapons and the concept of nuclear deterrence.

On February 7, 1964, Pan Am Yankee Clipper flight 101 from London Heathrow lands at New York’s Kennedy Airport—and “Beatlemania” arrives.

At approximately 8:12 p.m. Eastern time, Sunday, February 9, 1964, The Ed Sullivan Show returned from a commercial (for Anacin pain reliever), and there was Ed Sullivan standing before a restless crowd. He tried to begin his next introduction, but then stopped and extended his arms in the universal sign for “Settle Down.” “Quiet!” he said with mock gravity, and the noise died down just a little. Then he resumed: “Here’s a very amusing magician we saw in Europe and signed last summer….Let’s have a nice hand for him—Fred Kaps!”

On February 25, 1964, 22-year-old Cassius Clay shocks the odds-makers by dethroning world heavyweight boxing champ Sonny Liston in a seventh-round technical knockout. Former champ Joe Louis called it "the biggest upset in the history of boxing."

On February 27, 1964, the Italian government announces that it is accepting suggestions on how to save the renowned Leaning Tower of Pisa from collapse. The top of the 180-foot tower was hanging 17 feet south of the base, and studies showed that the tilt was increasing by a fraction every year. Experts warned that the medieval building—one of Italy’s top tourist attractions—was in serious danger of toppling in an earthquake or storm.

Jack Ruby, the Dallas nightclub owner who killed Lee Harvey Oswald—the accused assassin of President John F. Kennedy—is found guilty of the “murder with malice” of Oswald and sentenced to die in the electric chair. It was the first courtroom verdict to be televised in U.S. history.

The strongest earthquake in American history, measuring 9.2 on the Richter scale, slams southern Alaska, creating a deadly tsunami. Some 131 people were killed and thousands injured.

On April 13, 1964, Sidney Poitier becomes the first African American to win the Academy Award for Best Actor, for his role as a construction worker who helps build a chapel in Lilies of the Field (1963).

The Ford Mustang is officially unveiled by Henry Ford II at the World’s Fair in Flushing Meadows, New York, on April 17, 1964. That same day, the new car also debuted in Ford showrooms across America and almost 22,000 Mustangs were immediately snapped up by buyers. Named for a World War II fighter plane, the Mustang was one of the first vehicles that came to be known as a “pony car.” Ford sold more than 400,000 Mustangs within its first year of production, far exceeding sales expectations.

On May 9, 1964, the great Louis Armstrong, age 63, broke the Beatles’ stranglehold on the U.S. pop charts with the #1 hit “Hello Dolly.”

A referee’s call in a soccer match between Peru and Argentina sparks a riot on May 24, 1964. More than 300 fans were killed and another 500 people were injured in the violent melee that followed at National Stadium in Lima, Peru.

On May 28, 1964, the Palestine Liberation Organization was founded. In February of 1969, Yasir Arafat was elected as its leader. By 1974, when he addressed the United Nations, Arafat had made significant strides towards establishing new respectability for the PLO’s campaign for a Palestinian homeland. But gaining legitimacy hinged on cooling down terrorism, and Arafat found it increasingly difficult to reconcile the moderate and extremist segments of Palestinian politics.

Fifteen-year-old Alleen Rowe is killed by Charles Schmid in the desert outside Tucson, Arizona. Earlier in the night, Schmid allegedly had said to his friends, “I want to kill a girl! I want to do it tonight. I think I can get away with it!” Schmid went on to kill two other teenage girls before being caught by police.

A U.S. Navy jet flying low-altitude target reconnaissance missions over Laos is shot down by communist Pathet Lao ground fire. Less than 48 hours later, a second jet, which was escorting an unarmed reconnaissance aircraft, is also shot down.

In reply to a formal question submitted by President Lyndon B. Johnson—“Would the rest of Southeast Asia necessarily fall if Laos and South Vietnam came under North Vietnamese control?”—the Central Intelligence Agency (CIA) submits a memo that effectively challenges the “domino theory” backbone of the Johnson administration policies. This theory contended that if South Vietnam fell to the communists, the rest of Southeast Asia would also fall “like dominoes,” and the theory had been used to justify much of the Vietnam War effort.

At a meeting of the National Security Council, McGeorge Bundy, national security advisor to President Lyndon B. Johnson, informs those in attendance that President Johnson has decided to postpone submitting a resolution to Congress asking for authority to wage war.

Michael Schwerner, Andrew Goodman and James Chaney are killed by a Ku Klux Klan mob near Meridian, Mississippi. The three young civil rights workers were working to register Black voters in Mississippi, thus inspiring the ire of the local Klan. The deaths of Schwerner and Goodman, white Northerners and members of the Congress of Racial Equality (CORE), caused a national outrage.

On July 2, 1964, U.S. President Lyndon B. Johnson signs into law the historic Civil Rights Act in a nationally televised ceremony at the White House.

Senator Barry Goldwater (R-Arizona) is nominated by the Republican Party to run for president. During the subsequent campaign, Goldwater said that he thought the United States should do whatever was necessary to win in Vietnam. At one point, he talked about the possibility of using low-yield atomic weapons to defoliate enemy infiltration routes, but he never actually advocated the use of nuclear weapons in Southeast Asia. Although Goldwater later clarified his position, the Democrats very effectively portrayed him as a trigger-happy warmonger. This reputation, whether deserved or not, was a key factor in his crushing defeat at the hands of Lyndon B. Johnson, who won 61 percent of the vote to Goldwater’s 39 percent.

Ranger 7, an unmanned U.S. lunar probe, takes the first close-up images of the moon—4,308 in total—before it impacts with the lunar surface northwest of the Sea of Clouds. The images were 1,000 times as clear as anything ever seen through earth-bound telescopes.

The remains of three civil rights workers whose disappearance on June 21 garnered national attention are found buried in an earthen dam near Philadelphia, Mississippi. Michael Schwerner and Andrew Goodman, both white New Yorkers, had traveled to heavily segregated Mississippi in 1964 to help organize civil rights efforts on behalf of the Congress of Racial Equality (CORE). The third man, James Chaney, was a local African American man who had joined CORE in 1963. The disappearance of the three young men led to a massive FBI investigation that was code-named MIBURN, for “Mississippi Burning.”

The United States Congress overwhelming approves the Gulf of Tonkin Resolution, giving President Lyndon B. Johnson nearly unlimited powers to oppose “communist aggression” in Southeast Asia. The resolution marked the beginning of an expanded military role for the United States in the Cold War battlefields of Vietnam, Laos and Cambodia.

On August 12, 1964, Charlie Wilson, part of the gang who pulled off the 1963 Great Train Robbery, one of the biggest heists of its kind, escapes from Winson Green Prison in Birmingham, England. Several men broke into the maximum-security facility to free Wilson, who remained on the loose until 1968.

On August 12, 1964, the British author and journalist Ian Fleming, creator of James Bond, the world’s most famous fictional spy, dies of a heart attack at age 56 in Kent, England. Fleming’s series of novels about the debonair Agent 007, based in part on their dashing author’s real-life experiences, spawned one of the most lucrative film franchises in history.

On August 19, 1964, more than six months after taking the East Coast by storm, the Fab Four travel to California to take the stage at the Cow Palace in San Francisco for opening night of their first-ever concert tour of North America.

Lyndon B. Johnson is nominated to run for the presidency at the Democratic National Convention in Atlantic City, New Jersey. His running mate would be Hubert H. Humphrey. Former Vice President Johnson had assumed the reigns of government in November 1963 when President John F. Kennedy was assassinated. Upon assuming office, he inherited a commitment to Vietnam where Kennedy had sent military advisors to support the South Vietnamese government in Saigon.

On September 1, 1964, pitcher Masanori Murakami becomes the first Japanese man to play in U.S. baseball’s major leagues. Murakami pitched a scoreless eighth inning for the San Francisco Giants in a 4-1 loss to the New York Mets in front of 39,379 fans at Shea Stadium.

Writer John Steinbeck was presented the U.S. Medal of Freedom on September 14, 1964. Steinbeck had already received numerous other honors and awards for his writing, including the 1962 Nobel Prize and a 1939 Pulitzer Prize for Grapes of Wrath.

On September 14, 1964, the Kellogg’s Company begins selling the Pop-Tart. The innovative portable-breakfast-treat-turned-anytime-snack would go on to sell billions annually and help redefine the breakfast food market.

On September 24, 1964, President Lyndon B. Johnson receives a special commission’s report on the assassination of President John F. Kennedy, which had occurred on November 22, 1963, in Dallas, Texas.

The Soviet Union launches Voskhod 1 into orbit around Earth, with cosmonauts Vladamir Komarov, Konstantin Feoktistov, and Boris Yegorov aboard. Voskhod 1 was the first spacecraft to carry a multi-person crew, and the two-day mission was also the first flight performed without space suits.

In the midst of the conflict in Vietnam, Nikita Khrushchev is ousted as both premier of the Soviet Union and chief of the Communist Party after 10 years in power. He left office the next day, October 15, 1964. He was succeeded as head of the Communist Party by his former protégé Leonid Brezhnev, who would eventually become the chief of state as well.

African American civil rights leader Dr. Martin Luther King Jr., is awarded the Nobel Peace Prize for his nonviolent resistance to racial prejudice in America. At 35 years of age, the Georgia-born minister was the youngest person ever to receive the award.

The People’s Republic of China joins the rank of nations with atomic bomb capability, after a successful nuclear test on October 16, 1964. China is the fifth member of this exclusive club, joining the United States, the Soviet Union, Great Britain and France.

On October 22, 1964, Jean-Paul Sartre is awarded the Nobel Prize for literature, which he declines.

On October 25, 1964, after recovering a fumble against the 49ers in San Francisco, Minnesota Vikings star defensive end Jim Marshall runs 66 yards the wrong way into his own end zone. The four-year veteran believes he has scored a touchdown, so he throws the ball out of bounds in celebration, resulting in a safety for San Franscisco and putting an exclamation point on one of the worst gaffes in NFL history. Despite Marshall's error, the Vikings win, 27-22.

In one of the most crushing victories in the history of U.S. presidential elections, incumbent Lyndon Baines Johnson defeats Republican challenger Barry Goldwater, Sr. With more than 60 percent of the popular vote, Johnson turned back the conservative senator from Arizona to secure his first full term in office after succeeding to the presidency after the assassination of John F. Kennedy in November 1963.

On November 3, 1964, residents of the District of Columbia cast their ballots in a presidential election for the first time since 1800. The passage of the 23rd Amendment in 1961 gave citizens of the nation’s capital the right to vote for a commander in chief and vice president. They went on to help Democrat Lyndon Johnson defeat Republican Barry Goldwater in 1964, the next presidential election.

The first Medal of Honor awarded to a U.S. serviceman for action in Vietnam is presented to Capt. Roger Donlon of Saugerties, New York, for his heroic action earlier in the year.

On December 11, 1964, in response to a reported shooting, officers of the Los Angeles Police Department are dispatched to the Hacienda Motel, where they find musician Sam Cooke dead on the office floor, shot three times in the chest by the motel’s manager, Bertha Franklin. The authorities ruled Cooke’s death a case of justifiable homicide, based on the testimony of Ms. Franklin, who claimed that Cooke had threatened her life after attempting to rape a young woman with whom he had earlier checked in.

Two Viet Cong agents disguised as South Vietnamese soldiers leave a car filled with explosives parked at the Brinks Hotel in Saigon. The hotel was housing U.S. officers. Two Americans were killed in the blast and 65 Americans and Vietnamese were injured.

The Viet Cong launch a major offensive in the early morning hours of December 28, 1964 in the the village of Binh Gia, 40 miles southeast of Saigon. The bloody battle lasted until January 1, 1965, when Viet Cong forces abandoned the town.