On January 11, 1922, 14-year-old Leonard Thompson becomes the first person to receive an injection of the hormone insulin for Type-1 diabetes—a disease that for millennia had been considered a death sentence for anyone who developed it. The breakthrough would be one of the most consequential in medical history, saving millions of lives.

Police discover the body of film director William Desmond Taylor in his Los Angeles bungalow. Lieutenant Tom Ziegler responded to a call about a “natural death” at the Alvarado Street home of Taylor. When he arrived they found actors, actresses and studio executives rummaging through the director’s belongings. He also found Taylor lying on the living room floor with a bullet in his back—not exactly suggesting a “natural” death.

On February 4, 1922, the Ford Motor Company acquires the failing luxury automaker Lincoln Motor Company for $8 million.

In deciding the case Leser v. Garnett, the U.S. Supreme Court upholds the constitutionality of the 19th Amendment—which, when ratified two years earlier, provided American women with the right to vote. The justices were unanimous in their decision to dismiss the challenge.

After years of being repeatedly arrested and detained by his country’s British colonial government for his leadership activity in India’s independence movement, activist and spiritual leader Mohandas Karamchand Gandhi is arrested on March 10, 1922 in Bombay on his most serious charge yet: sedition. Gandhi—nicknamed Mahatma, which means “the great-souled one”—is sentenced to six years in prison for protesting the British colonial government.

Former President William Howard Taft dedicates the Lincoln Memorial on the Washington Mall on May 30, 1922. At the time, Taft was serving as chief justice of the U.S. Supreme Court. A crowd gathered on the Mall to witness the ceremony.

On May 30, 1922, President Warren G. Harding becomes the first president to have his voice transmitted by radio while addressing a crowd at the dedication of the Lincoln Memorial. The broadcast heralded a revolutionary shift in how presidents addressed the American public. It was not until three years later, however, that a president would deliver a radio-specific address. That honor went to President Calvin Coolidge.

On June 27, 1922, the American Library Association (ALA) awards the first Newbery Medal, honoring the year’s best children’s book, to The Story of Mankind by Hendrik Willem van Loon. The idea for an award honoring outstanding contributions to children’s literature came from Frederic G. Melcher, a former bookseller who in 1918 became an editor of Publisher’s Weekly. Over his long career, Melcher often looked for ways to encourage reading, especially among children. In 1919, he co-founded Children’s Book Week with Franklin K. Mathiews, librarian of the Boy Scouts organization. Two years later, Melcher suggested the creation of a children’s book award at a June 1921 meeting of the Children’s Librarians’ Section of the ALA. He proposed that it should be named for John Newbery, the 18th-century English bookseller and author who was considered the father or ”inventor” of children’s literature.

Irish revolutionary and Sinn Fein politician Michael Collins is killed in an ambush in west County Cork, Ireland.

British archaeologist Howard Carter and his workmen discover a step leading to the tomb of King Tutankhamen in the Valley of the Kings in Egypt on November 4, 1922.

In Egypt’s Valley of the Kings, British archaeologists Howard Carter and Lord Carnarvon become the first souls to enter King Tutankhamen’s tomb in more than 3,000 years. Tutankhamen’s sealed burial chambers were miraculously intact, and inside was a collection of several thousand priceless objects, including a gold coffin containing the mummy of the teenage king.

On December 10, 1922, the Canton Bulldogs defeat the Toledo Maroons, 19-0, and are declared the first champion of the newly renamed National Football League. Canton finishes the season 10-0-2, allowing 15 points and producing nine shutouts. The league champion is determined by best regular-season record.

On December 30, 1922, in post-revolutionary Russia, the Union of Soviet Socialist Republics (USSR) is established, comprising a confederation of Russia, Belorussia, Ukraine and the Transcaucasian Federation (divided in 1936 into the Georgian, Azerbaijan and Armenian republics). Also known as the Soviet Union, the new communist state was the successor to the Russian Empire and the first country in the world to be based on Marxist socialism.